New technology in Alzheimer's diagnosis

New technology in Alzheimer's diagnosis

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Alzheimer hastalığının teşhisi, hastalığın seyri ve tedavi süreci açısından büyük önem taşımaktadır. Alzheimer'ın beyinde nörofibriller yumak ve beta amiloid plakları adı verilen maddelerin birikmesiyle oluştuğunu belirten uzmanlar, bu maddelerin yeni tanı yöntemleriyle tespit edilebileceğini ifade etmektedir. Amyloid PET adı verilen tomografi benzeri bir testin, bu maddelerden biri olan amiloid plakların birikip birikmediğini kolayca gösterebileceğini belirten Nöroloji Uzmanı Dr. Celal Şalçini, amiloid plakların görünmediği durumlarda hastaya "Alzheimer hastalığınız yok" diyebildiklerini belirtmiştir. Alzheimer, ilerleyici bir beyin hastalığı olup genellikle ileri yaşlarda görülse de orta ve genç yaşlarda da başlayabilir ve belirsiz bir unutkanlıkla başlayıp sinsice ilerleyerek belirgin hale gelir. Yeni tanı yöntemlerinden biri olan Amyloid PET cihazı, Alzheimer şüphesi olan ve aile öyküsü bulunan bireylerde amiloid plak birikimini tespit ederek hastalığın erken teşhisine ve kesinleşmemesine olanak sağlar.

Diagnosis of Alzheimer's disease, which is widely encountered today, is of great importance in terms of the course of the disease and the treatment process. Noting that Alzheimer's disease is caused by the accumulation of substances called neurofibrillary tangles and beta amyloid plaques in the brain, experts state that these substances can be detected with new diagnostic methods. Stating that a tomography-like test called Amyloid PET can easily show whether there is an accumulation of amyloid plaques, one of these substances, Neurology Specialist Celal Şalçini said, "In cases where amyloid plaques are not visible, we can now say to the patient 'You do not have Alzheimer's disease'."

Üsküdar University NPISTANBUL Hospital Neurology Specialist Dr. Celal Şalçini noted that the accumulation of substances that cause Alzheimer's disease in the brain can be detected with the help of a tomography-like device called Amyloid PET.

Alzheimer's is an insidious brain disease

Dr. Celal Şalçini noted that Alzheimer's disease is a progressive brain disease that is usually observed in advanced ages and can also start in middle and young ages, and said, "Alzheimer's disease starts with a vague forgetfulness and progresses insidiously until it becomes obvious."

It occurs when substances accumulate in the brain

Prof. Dr. Celal Şalçini said, "Alzheimer's disease is caused by the accumulation of substances we call neurofibrillary tangles and beta amyloid plaques in the brain, and this accumulation begins long before Alzheimer's Disease is evident. In the diagnosis of Alzheimer's Disease and similar dementias, it may be necessary to demonstrate the accumulation of these substances in the brain. In these cases, brain tissue sampling or spinal fluid examination can be performed, but both are not preferred because they are interventional procedures."

Alzheimer's can be detected with amyloid PET device

Stating that new diagnostic methods are used in Alzheimer's diagnosis with developing technologies, Dr. Celal Şalçini said, "The accumulation of amyloid plaques, one of these substances, can be easily shown with a tomography-like device called Amyloid PET, which has recently started to be used in Turkey. In this way, Amyloid PET is performed on individuals who are suspected of Alzheimer's Disease due to forgetfulness and who also have a family history of Alzheimer's Disease, and Alzheimer's Disease is excluded if no amyloid plaque is observed."

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CreatorNP Istanbul Hospital Editorial Board
Updated At23 January 2025
Created At21 January 2021
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