What is Creatinine?

What is Creatinine?

It is a chemical waste product caused by the wear and tear of the muscles in the human body. It is filtered through the kidneys and excreted through urine. The level in the blood varies according to the age, gender and muscle mass of the person. For this reason, it can be found at higher levels in men than in women.

Creatinine is generally produced in the muscles in the body. Since the production is linked to the muscles, creatinine values are high in individuals with dense muscle mass. Low creatinine levels are more common in the elderly, weak and people with low muscle mass.

What Does High Creatinine Mean?

It varies according to the age, gender and muscle mass of the person and in some cases its value increases. Damage to the kidney, failure to fulfill its functions, insufficient filtering of wastes cause the value in the blood to increase. As a result of the tests, kidney problems are found in people with high values. People experience symptoms such as weakness and loss of appetite. If the kidneys do not work, they cannot remove water and water remains in the body. This leads to swelling of some parts of the body. An elevated creatinine value can be a sign of the disease. Patients can be treated by applying to nephrology or internal medicine departments.
Related symptoms and causes are as follows:
Kidney Infection: It is also known as pyelonephritis. It is a type of urinary tract infection. It occurs when viruses and bacteria cause infection. Symptoms such as fever, burning and odor in urine, nausea, vomiting, pain in the back and sides, groin pain, bloody urine are considered sufficient for suspicion of pyelonephritis.
Diabetes Diabetes causes problems in the kidneys as well as many other problems. Diabetes, which has 2 types, mostly causes symptoms such as urinary frequency, fatigue, increased appetite, numbness of hands and feet.
High Blood Pressure: High blood pressure, which can damage the veins around the kidney and affect the kidney's ability to perform its functions, can cause an increase in the value in the body.
Heart Diseases: A number of cardiovascular diseases can also cause problems in the kidneys. Poor blood flow to the kidneys can cause long-term damage. Arteriosclerosis usually does not occur unless there are major blockages. In some cases, however, it can cause symptoms such as chest pain, shortness of breath, tiredness and sometimes difficulty speaking. In heart failure, there may be difficulty breathing, or shortness of breath, fatigue, swelling in the feet and legs.
Urinary Tract Blockage: The urinary tract can become blocked for a number of reasons such as prostate, kidney stones and tumors. In such cases, urine can collect in the kidneys. An increase in the rate of the value in the urine leads to urinary tract obstruction. Symptoms include fatigue, back pain, blood in the urine and pain.
Kidney Failure: Elevated levels are more common here. There may be symptoms such as fatigue, nausea, loss of consciousness, headache, insomnia, muscle cramps.

What is creatinine low?

Its low level is determined by tests just like its high level. Symptoms vary depending on the cause of the low level. Causes and symptoms can be listed as follows:
Low Muscle Mass: Since the muscles have a direct effect on the value in the body, people with low muscle mass have a decrease in their values. A decrease in muscle mass varying according to gender and age can lead to a decrease in values. Irregular and adequate nutrition can be a factor in muscle mass. For this reason, attention should be paid to a healthy and adequate diet. It is also possible for this value to decrease in important and dangerous muscle diseases. Symptoms include pain, stiffness, weakness and reduction in muscle mass.
Weight Loss: People who experience excessive weight loss also experience a decrease in the muscles in their body. In this case, the values may be low.
Pregnancy: During pregnancy, blood flow in the kidneys increases. This increases the level of creatinine excreted from the body.

What is the Normal Value of Creatinine?

It is directly related to the muscles in the body. Its level in the blood shows the muscle density and kidney function of people. The level seen in adult men with normal kidney function is approximately 07-1.3 milligrams and 0.6-1.1 milligrams for women. The lower level in women is related to floor mass.

Creatinine Test

Creatinine can be detected by tests when it is present at high or low levels in the body. This test, which is performed with samples taken from blood and urine, also determines the condition of the kidneys and how well they are functioning.

Low and High Creatinine in Urine

It needs to be treated depending on the factors that cause low and high urine levels. The level in the body is determined as a result of tests performed with samples taken from urine or blood. These levels reveal the kidney health of the person. When high levels are seen due to kidneys, a treatment method is applied. At low levels, the person needs to increase muscle mass and eat a healthy and balanced diet.

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Updated At05 March 2024
Created At15 September 2022
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